Northwest Biophysics Consortium

Publication Listing for Trushar Patel

• Solution Structure of C. elegans UNC-6: A Nematode Paralogue of the Axon Guidance Protein Netrin-1.
  Krahn N, Meier M, Reuten R, Koch M, Stetefeld J, Patel TR
  Biophys J: 2019-06-04; 116(11); 2121-2130     Epub: 2019-05-03.
  PMID: 31103237    LINK: https://www.ncbi.nlm.nih.gov/pubmed/31103237
• Crystal structure of the TreS:Pep2 complex, initiating α-glucan synthesis in the GlgE pathway of mycobacteria.
  Kermani AA, Roy R, Gopalasingam C, Kocurek KI, Patel TR, Alderwick LJ, Besra GS, Fütterer K
  J Biol Chem: 2019-05-03; 294(18); 7348-7359     Epub: 2019-03-15.
  PMID: 30877199    LINK:
• Current approaches for RNA labelling to identify RNA-binding proteins.
  Gemmill D, D
  Biochem Cell Biol: 2019-03-30; ();     Epub: 2019-03-30.
  PMID: 30931575    LINK: https://www.ncbi.nlm.nih.gov/pubmed/30931575
• A Cholesterol Analog Induces an Oligomeric Reorganization of VDAC.
  Ferens FG, Patel TR, Oriss G, Court DA, Stetefeld J
  Biophys J: 2019-03-05; 116(5); 847-859     Epub: 2019-02-01.
  PMID: 30777305    LINK:
• Structural Studies of Macromolecules in Solution using Small Angle X-Ray Scattering.
  Mrozowich T, McLennan S, Overduin M, Patel TR
  J Vis Exp: 2018-11-05; (141);     Epub: 2018-11-05.
  PMID: 30451239    LINK:
• Comprehensive Analysis of Hepatitis B Virus Promoter Region Mutations.
  Meier-Stephenson V, Bremner WTR, Dalton CS, van Marle G, Coffin CS, Patel TR
  Viruses: 2018-11-01; 10(11);     Epub: 2018-11-01.
  PMID: 30388827    LINK: https://www.ncbi.nlm.nih.gov/pubmed/30388827
• Interaction studies of a protein and carbohydrate system using an integrated approach: a case study of the miniagrin-heparin system.
  Patel TR, Besong TMD, Meier M, McEleney K, Harding SE, Winzor DJ, Stetefeld J
  Eur Biophys J: 2018-10-01; 47(7); 751-759     Epub: 2018-03-12.
  PMID: 29532137    LINK:
• Analytical ultracentrifugation (AUC): a seminal tool offering multiple solutions.
  Byron O, Nischang I, Patel TR
  Eur Biophys J: 2018-10-01; 47(7); 693-696
  PMID: 30218114    LINK:
• The role of zyxin in regulation of malignancies.
  Kotb A, Hyndman ME, Patel TR
  Heliyon: 2018-07-01; 4(7); e00695     Epub: 2018-07-18.
  PMID: 30094365    LINK:
• Structure and hydrodynamics of a DNA G-quadruplex with a cytosine bulge.
  Meier M, Moya-Torres A, Krahn NJ, McDougall MD, Orriss GL, McRae EKS, Booy EP, McEleney K, Patel TR, McKenna SA, Stetefeld J
  Nucleic Acids Res: 2018-06-01; 46(10); 5319-5331
  PMID: 29718405    LINK:
• Allowance for radial dilution in evaluating the concentration dependence of sedimentation coefficients for globular proteins.
  Patel TR, Winzor DJ, Scott DJ
  Eur Biophys J: 2018-04-01; 47(3); 291-295     Epub: 2017-10-04.
  PMID: 28980105    LINK:
• Viral proteins targeting host protein kinase R to evade an innate immune response: a mini review.
  Dzananovic E, McKenna SA, Patel TR
  Biotechnol Genet Eng Rev: 2018-04-01; 34(1); 33-59     Epub: 2018-05-02.
  PMID: 29716441    LINK:
• Proceedings of the Alberta Virology Conference, University of Alberta, 1-2 June 2017; edited by Guido van Marle and Trushar R. Patel_{Virology in Alberta and Canada}.
  van Marle G, Patel TR
  Biotechnol Genet Eng Rev: 2018-04-01; 34(1); 1-2
  PMID: 29895238    LINK:
• DEAD-box helicases: the Yin and Yang roles in viral infections.
  Meier-Stephenson V, Mrozowich T, Pham M, Patel TR
  Biotechnol Genet Eng Rev: 2018-04-01; 34(1); 3-32     Epub: 2018-05-09.
  PMID: 29742983    LINK:
• Non-coding RNAs in virology: an RNA genomics approach.
  Isaac C, Patel TR, Zovoilis A
  Biotechnol Genet Eng Rev: 2018-04-01; 34(1); 90-106     Epub: 2018-06-04.
  PMID: 29865927    LINK:
• Nanoscale Assembly of High-Mobility Group AT-Hook 2 Protein with DNA Replication Fork.
  Krahn N, Meier M, To V, Booy EP, McEleney K, O'Neil JD, McKenna SA, Patel TR, Stetefeld J
  Biophys J: 2017-12-19; 113(12); 2609-2620
  PMID: 29262356    LINK:
• Intrinsic disorder in the partitioning protein KorB persists after co-operative complex formation with operator DNA and KorA.
  Hyde EI, Callow P, Rajasekar KV, Timmins P, Patel TR, Siligardi G, Hussain R, White SA, Thomas CM, Scott DJ
  Biochem J: 2017-08-30; 474(18); 3121-3135     Epub: 2017-08-30.
  PMID: 28760886    LINK:
• Structural studies of RNA-protein complexes: A hybrid approach involving hydrodynamics, scattering, and computational methods.
  Patel TR, Chojnowski G, Astha, Koul A, McKenna SA, Bujnicki JM
  Methods: 2017-04-15; 118-119(); 146-162     Epub: 2016-12-08.
  PMID: 27939506    LINK:
• Application of novel analytical ultracentrifuge analysis to solutions of fungal mannans.
  Gillis RB, Adams GG, Besong DT, Machová E, Ebringerová A, Rowe AJ, Harding SE, Patel TR
  Eur Biophys J: 2017-04-01; 46(3); 235-245     Epub: 2016-07-21.
  PMID: 27444285    LINK:
• Inhibition of glycosylation on a camelid antibody uniquely affects its FcγRI binding activity.
  Krahn N, Spearman M, Meier M, Dorion-Thibaudeau J, McDougall M, Patel TR, De Crescenzo G, Durocher Y, Stetefeld J, Butler M
  Eur J Pharm Sci: 2017-01-01; 96(); 428-439     Epub: 2016-10-07.
  PMID: 27721040    LINK:
• Dynamic light scattering: a practical guide and applications in biomedical sciences.
  Stetefeld J, McKenna SA, Patel TR
  Biophys Rev: 2016-12-01; 8(4); 409-427     Epub: 2016-10-06.
  PMID: 28510011    LINK:
• Structural decoding of netrin-4 reveals a regulatory function towards mature basement membranes.
  Reuten R, Patel TR, McDougall M, Rama N, Nikodemus D, Gibert B, Delcros JG, Prein C, Meier M, Metzger S, Zhou Z, Kaltenberg J, McKee KK, Bald T, Tüting T, Zigrino P, Djonov V, Bloch W, Clausen-Schaumann H, Poschl E, Yurchenco PD, Ehrbar M, Mehlen P,
  Nat Commun: 2016-11-30; 7(); 13515     Epub: 2016-11-30.
  PMID: 27901020    LINK:
• LAR protein tyrosine phosphatase regulates focal adhesions through CDK1.
  Sarhan AR, Patel TR, Cowell AR, Tomlinson MG, Hellberg C, Heath JK, Cunningham DL, Hotchin NA
  J Cell Sci: 2016-08-01; 129(15); 2962-71     Epub: 2016-06-27.
  PMID: 27352860    LINK:
• Regulation of Platelet Derived Growth Factor Signaling by Leukocyte Common Antigen-related (LAR) Protein Tyrosine Phosphatase: A Quantitative Phosphoproteomics Study.
  Sarhan AR, Patel TR, Creese AJ, Tomlinson MG, Hellberg C, Heath JK, Hotchin NA, Cunningham DL
  Mol Cell Proteomics: 2016-06-01; 15(6); 1823-36     Epub: 2016-04-13.
  PMID: 27074791    LINK:
• Analytical ultracentrifugation: A versatile tool for the characterisation of macromolecular complexes in solution.
  Patel TR, Winzor DJ, Scott DJ
  Methods: 2016-02-15; 95(); 55-61     Epub: 2015-11-10.
  PMID: 26555086    LINK:
• Structural Decoding of the Netrin-1/UNC5 Interaction and its Therapeutical Implications in Cancers.
  Grandin M, Meier M, Delcros JG, Nikodemus D, Reuten R, Patel TR, Goldschneider D, Orriss G, Krahn N, Boussouar A, Abes R, Dean Y, Neves D, Bernet A, Depil S, Schneiders F, Poole K, Dante R, Koch M, Mehlen P, Stetefeld J
  Cancer Cell: 2016-02-08; 29(2); 173-85
  PMID: 26859457    LINK:
• Biophysical analysis of a lethal laminin alpha-1 mutation reveals altered self-interaction.
  Patel TR, Nikodemus D, Besong TMD, Reuten R, Meier M, Harding SE, Winzor DJ, Koch M, Stetefeld J
  Matrix Biol: 2016-01-01; 49(); 93-105     Epub: 2015-07-26.
  PMID: 26215696    LINK:
• Characterization of the termini of the West Nile virus genome and their interactions with the small isoform of the 2' 5'-oligoadenylate synthetase family.
  Deo S, Patel TR, Chojnowski G, Koul A, Dzananovic E, McEleney K, Bujnicki JM, McKenna SA
  J Struct Biol: 2015-05-01; 190(2); 236-49     Epub: 2015-04-11.
  PMID: 25871524    LINK:
• Molecular dissection of Wnt3a-Frizzled8 interaction reveals essential and modulatory determinants of Wnt signaling activity.
  Kumar S, Žigman M, Patel TR, Trageser B, Gross JC, Rahm K, Boutros M, Gradl D, Steinbeisser H, Holstein T, Stetefeld J, Özbek S
  BMC Biol: 2014-05-30; 12(); 44     Epub: 2014-05-30.
  PMID: 24885675    LINK:
• Conformational itinerary of Pseudomonas aeruginosa 1,6-anhydro-N-acetylmuramic acid kinase during its catalytic cycle.
  Bacik JP, Tavassoli M, Patel TR, McKenna SA, Vocadlo DJ, Khajehpour M, Mark BL
  J Biol Chem: 2014-02-14; 289(7); 4504-14     Epub: 2013-12-20.
  PMID: 24362022    LINK:
• Structural elucidation of full-length nidogen and the laminin-nidogen complex in solution.
  Patel TR, Bernards C, Meier M, McEleney K, Winzor DJ, Koch M, Stetefeld J
  Matrix Biol: 2014-01-01; 33(); 60-7     Epub: 2013-08-12.
  PMID: 23948589    LINK:
• Solution conformation of adenovirus virus associated RNA-I and its interaction with PKR.
  Dzananovic E, Patel TR, Chojnowski G, Boniecki MJ, Deo S, McEleney K, Harding SE, Bujnicki JM, McKenna SA
  J Struct Biol: 2014-01-01; 185(1); 48-57     Epub: 2013-11-28.
  PMID: 24291322    LINK:
• Binding of G-quadruplexes to the N-terminal recognition domain of the RNA helicase associated with AU-rich element (RHAU).
  Meier M, Patel TR, Booy EP, Marushchak O, Okun N, Deo S, Howard R, McEleney K, Harding SE, Stetefeld J, McKenna SA
  J Biol Chem: 2013-12-06; 288(49); 35014-27     Epub: 2013-10-22.
  PMID: 24151078    LINK:
• C1q-tumour necrosis factor-related protein 8 (CTRP8) is a novel interaction partner of relaxin receptor RXFP1 in human brain cancer cells.
  Glogowska A, Kunanuvat U, Stetefeld J, Patel TR, Thanasupawat T, Krcek J, Weber E, Wong GW, Del Bigio MR, Hoang-Vu C, Hombach-Klonisch S, Klonisch T
  J Pathol: 2013-12-01; 231(4); 466-79
  PMID: 24014093    LINK:
• A potential for overestimating the absolute magnitudes of second virial coefficients by small-angle X-ray scattering.
  Scott DJ, Patel TR, Winzor DJ
  Anal Biochem: 2013-04-15; 435(2); 159-65     Epub: 2013-01-10.
  PMID: 23313340    LINK:
• Recognition of viral RNA stem-loops by the tandem double-stranded RNA binding domains of PKR.
  Dzananovic E, Patel TR, Deo S, McEleney K, Stetefeld J, McKenna SA
  RNA: 2013-03-01; 19(3); 333-44     Epub: 2013-01-17.
  PMID: 23329698    LINK:
• Determination of a molecular shape for netrin-4 from hydrodynamic and small angle X-ray scattering measurements.
  Patel TR, Reuten R, Xiong S, Meier M, Winzor DJ, Koch M, Stetefeld J
  Matrix Biol: 2012-03-01; 31(2); 135-40     Epub: 2011-12-24.
  PMID: 22210009    LINK:
• The macromolecular state of A-kinase anchoring protein.
  Patel TR, Winzor DJ
  J Mol Recognit: 2012-01-01; 25(1); 11-4
  PMID: 22213446    LINK:
• Evidence for self-association of a miniaturized version of agrin from hydrodynamic and small-angle X-ray scattering measurements.
  Patel TR, Besong TM, Patel N, Meier M, Harding SE, Winzor DJ, Stetefeld J
  J Phys Chem B: 2011-09-29; 115(38); 11286-93     Epub: 2011-09-07.
  PMID: 21859138    LINK:
• Examination of the discrepancy between size estimates for ovalbumin from small-angle X-ray scattering and other physicochemical measurements.
  Scott DJ, Patel TR, Besong DM, Stetefeld J, Winzor DJ
  J Phys Chem B: 2011-09-15; 115(36); 10725-9     Epub: 2011-08-22.
  PMID: 21793570    LINK:
• T-shaped arrangement of the recombinant agrin G3-IgG Fc protein.
  Patel TR, Meier M, Li J, Morris G, Rowe AJ, Stetefeld J
  Protein Sci: 2011-06-01; 20(6); 931-40     Epub: 2011-04-26.
  PMID: 21448912    LINK:
• Reassessment of the size of the supermolecular state of Dishevelled-3.
  Patel TR, Winzor DJ
  J Mol Recognit: 0000-00-00; 24(5); 843-6
  PMID: 21812058    LINK:
• Impact of the structural integrity of the three-way junction of adenovirus VAI RNA on PKR inhibition.
  Dzananovic E, Astha, Chojnowski G, Deo S, Booy EP, Padilla-Meier P, McEleney K, Bujnicki JM, Patel TR, McKenna SA
  PLoS One: 0000-00-00; 12(10); e0186849     Epub: 2017-10-20.
  PMID: 29053745    LINK:
• Activation of 2' 5'-oligoadenylate synthetase by stem loops at the 5'-end of the West Nile virus genome.
  Deo S, Patel TR, Dzananovic E, Booy EP, Zeid K, McEleney K, Harding SE, McKenna SA
  PLoS One: 0000-00-00; 9(3); e92545     Epub: 2014-03-20.
  PMID: 24651762    LINK:
• Biophysical Characterization of G-Quadruplex Recognition in the PITX1 mRNA by the Specificity Domain of the Helicase RHAU.
  Ariyo EO, Booy EP, Patel TR, Dzananovic E, McRae EK, Meier M, McEleney K, Stetefeld J, McKenna SA
  PLoS One: 0000-00-00; 10(12); e0144510     Epub: 2015-12-09.
  PMID: 26649896    LINK:
• Maltose-Binding Protein (MBP), a Secretion-Enhancing Tag for Mammalian Protein Expression Systems.
  Reuten R, Nikodemus D, Oliveira MB, Patel TR, Brachvogel B, Breloy I, Stetefeld J, Koch M
  PLoS One: 0000-00-00; 11(3); e0152386     Epub: 2016-03-30.
  PMID: 27029048    LINK:
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  PMID:    LINK:
• Site specific cleavage mediated by MMPs regulates function of agrin.
  Patel TR, Butler G, McFarlane A, Xie I, Overall CM, Stetefeld J
  PLoS One: 0000-00-00; 7(9); e43669     Epub: 2012-09-11.
  PMID: 22984437    LINK: